名稱 | Recombinant Human G-CSF |
型號 | |
更新時間 | 2023-09-24 |
特點 | g - csf的造血生長因子刺激承諾祖細(xì)胞中性粒細(xì)胞的發(fā)展和增強(qiáng)的功能活動end-cell成熟。產(chǎn)生針對特定的刺激多種細(xì)胞包括巨噬細(xì)胞、成纖維細(xì)胞、內(nèi)皮細(xì)胞和骨髓基質(zhì)。使用g - csf臨床上促進(jìn)骨髓移植后造血恢復(fù)。} |
產(chǎn)品展示 / PRODUCTS
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一.產(chǎn)品名稱:Recombinant Human G-CSF
二.Catalog Number:300-23
Synonyms:
Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin
Description:
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
AA Sequence:
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIW MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Cross Reactivity:
Monkey, Mouse, Pig, Human, Plant
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