名稱 | Recombinant Human IL-3 |
型號 | |
更新時間 | 2023-09-24 |
特點 | Peprotech IL-3造血生長因子,促進生存、分化和增殖的巨核細胞的祖細胞。激活單核細胞的能力表明IL-3可能有額外的免疫調(diào)節(jié)作用。許多IL-3活動取決于co-stimulation與其他細胞因子。重組人類IL-3 15.0 kDa球狀蛋白質(zhì)含有133個氨基酸殘基。。使用所有無動物生產(chǎn)試劑。} |
產(chǎn)品展示 / PRODUCTS
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一.產(chǎn)品名稱:Recombinant Human IL-3/Peprotech IL-3
二.Catalog Number:AF-200-03
三.Synonyms:MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
四.Description:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues. . Manufactured using all non-animal reagents.
五.AA Sequence:
APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQATTLSL AIF
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
九.Cross Reactivity:Monkey, Human + Mouse, Human, Mouse
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